Estefanía Tarifeño-Saldivia
Coordinadora Área Neurociencia
Grados:
Doctor en Ciencias, Université de Liège, Bélgica
Biologist, Universidad de Concepción, Chile.
BSc in Biology, Universidad de Concepción, Highest Honor.
Líneas de investigación
- (1) Estudiar los efectos epigenéticos de la obesidad en las neuronas que regulan el comportamiento alimenticio y la búsqueda de estrategias eficientes de pérdida de peso que reviertan estos efectos.
- (2) Identificar marcadores epigenéticos para el diagnóstico temprano de la depresión
- (3) Explorar el proteoma en contextos diversos como herramienta para el desarrollo tecnológico
Publicaciones destacadas
- Venegas, S., Alarcón, C., Araya, J., Gatica, M., Morin, V., Tarifeño-Saldivia, E., & Uribe, E. (2024). Biodegradation of Polystyrene by Galleria mellonella: Identification of Potential Enzymes Involved in the Degradative Pathway. International Journal of Molecular Sciences, 25(3), 1576. Doi: 10.3390/ijms25031576
- Amigo, R., Raiqueo, F., Tarifeño, E., Farkas, C., & Gutiérrez, J. L. (2023). Poly (dA: dT) tracts differentially modulate nucleosome remodeling activity of RSC and ISW1a complexes, exerting tract orientation-dependent and-independent effects. International Journal of Molecular Sciences, 24(20), 15245. Doi: 10.3390/ijms242015245
- Apablaza, H., Solís, M., Conejera, D., Fonseca, A., Cid, J., Tarifeño-Saldivia, E., … & Fernández, M. (2022). bHLH Transcription Factors Undergo Alternative Splicing During Cold Acclimation in a Eucalyptus hybrid. Plant Molecular Biology Reporter, 40(2), 310-326. Doi: 10.1007/s11105-021-01313-7
- Amigo, R., Farkas, C., Gidi, C., Hepp, M. I., Cartes, N., Tarifeño, E., … & Gutiérrez, J. L. (2021). The linker histone Hho1 modulates the activity of ATP-dependent chromatin remodeling complexes. Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms, 1865(1), 194781. Doi: 10.1016/j.bbagrm.2021.194781
- Salgado, M., Elizondo-Vega, R., Villar, P. S., Konar, M., Gallegos, S., Tarifeño-Saldivia, E., … & García-Robles, M. Á. (2022). GKRP-dependent modulation of feeding behavior by tanycyte-released monocarboxylates. Theranostics, 12(4), 1518-1536. Doi: 10.7150/thno.66634
Proyectos destacados
Millennium Nucleus on Tissue Self-Organisation and Mechanics (SELFO). Núcleo milenio en ciencias naturales y exactas 2024. ANID. Role: Principal Investigator. 2024-2028
Unraveling the Impact of Weight Loss on POMC Neurons in ObeseMice: Exploring Responses, Epigenetic Dynamics and Rebound Resistance. Fondecyt Regular. Project N°1241887: Role: Principal Investigator. 2024-2028
Unveiling long-term effects of obesity in neurons that suppress appetite: A genome-wide survey on the methylome of POMC neurons. University of Concepción. Project N°: 2023000755INV. Role: Principal Investigator. 2023-2025
Local Metabolic Signals Produced By Tanycytes Modulate Short- And Long-term Feeding Behavior Source: Fondecyt /ANID. Program: Fondecyt Regular. Project N°: 1221508. Role: Co-Investigator. 2022-2026
How do dietary choices during adolescence affect architecture, behaivor and epigenetics of the brain? Source: Interstellar Initiative, funded by Japan Agency for Medical Research and Development (AMED) and The new York Academy of Science (NYAS). Role: Co-Investigator. 2022-2023
Análisis Del Efecto Protector De La Nuez Mariposa En El Transcriptoma De Las Neuronas Pomc De Ratón Frente A Una Dieta Alta En Grasas. Source: Internal funding – VRID UdeC. Program: VRID Iniciación. Project N°: 2022.000.435-INI. Role: Co-Investigator. 2022-2024
Erasmus+ International Mobility staff. Source: Erasmus+ Mobility. Purpose: Funding for scientific and academic collaborations with the University of Liege. Role: Co-Investigator. 2021-2022
Desarrollo de una herramienta molecular para la bio-degradación de poliestireno (PS). Source: Internal funding – VRID UdeC. Program: VRID Multidisciplinario. Project N°: 220.037.026-M. Role: Co-Investigator. 2020-2021
Epigenetic re-programming induced by obesity on hypothalamic POMC neurons. Source: Internal funding – VRID UdeC. Program: VRID Iniciación. Project N°: 218.037.024-INI. Role: Principal Investigator. 2019-2020